Welcome to Verma Research Lab
The Verma Group is investigating novel biomaterials and controlled release delivery vehicles for needle-free targeted delivery of drugs, peptides, nucleic acids and vaccines. This group is working on developing non-invasive drug delivery technologies and pharmaceutical products based on these technologies. This involves designing, development and evaluation of polymeric nanoparticles and liposome-based formulations. In particular, this laboratory is currently focusing on research of aerosol-drug delivery systems ranging from powder production by novel processes, particle engineering and aerosol formulation. Group is also interested in nanoscale manipulation of multiphase polymeric materials and development of bio-inspired materials. Our expertise includes scalable formulation development using spray drying, Spray freeze-drying, supercritical fluid technology and microfluizider. We also conduct research in preclinical pharmacokinetic, therapeutic and toxicological evaluation in cells lines and animal models.
Dr. Rahul K. Verma, PhD.
MEDIA COVERAGE OF OUR RESEARCH
BLOGS
INST scientists develop hierarchically porous inhalable microspheres for efficient pulmonary delivery
INDIA DST-Blog Department of Science and technology, Government of India
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7 February 2017
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It has always been challenging to prepare polymeric microspheres (MS) with controlled porous structures for bio-therapeutic applications. Due to the irregular porous structure in micro-matrix and inhomogeneous particle size, controlled and sustained release to drugs is always a daunting task. Especially for pulmonary delivery, control over particle size (1–5 μm) and optimal porosity is extremely crucial for efficient release of drug to the lungs. Dr. Rahul Verma et al. from Institute of Nano Science and Technology, Mohali recently developed an elegant strategy to design hierarchically porous polymer microspheres with variable pore architecture for controlled delivery of a variety of loaded biotherapeutic molecules of different sizes. They used precisely optimized concentrations of several types of porogens/osmogens to specifically control the porosity and size of the micromatrix which are important parameters to make them inhalable.
UPCOMING EVENTS
Drug Delivery to Lungs (DDL-2017)
Edinburg, Scotland
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6-8 December
